Prof. Sanjar Madrakhimov

• Retinal diseases
• Age-related macular degeneration
• Diabetic retinopathy

• Ophthalmology, Tashkent Medical Academy, 2015-2016

Mar. 2022

International Medical Training Program

Advanced Cataract Training Program

International Academy Of Medical Education, Moscow, Russian Federation

Oct. 2017 – Mar. 2018

International Medical Training Program

Surgical retina

Soonchunhyang University Hospital Bucheon, Bucheon, South Korea

Jun. 2015 – Oct. 2015

Surgical Training

Cataract and refractive surgery

Spectra Eye Hospital , New-Delhi, India

1. Lee, S. H., Han, J. W., Yang, J. Y., Jun, H. O., Bang, J. H., Shin, H., Choi, J. H., Lee, J., Madrakhimov, S. B., Chung, K. H., Chang, H. S., Lyu, J., & Park, T. K. (2022). Role of mTORC1 activity during early retinal development and lamination in human-induced pluripotent stem cell‐derived retinal organoids. Cell Death Discovery, 8(1), 56. https://doi.org/10.1038/s41420-022-00837-5
2. Madrakhimov, S. B., Yang, J. Y., Ahn, D. H., Han, J. W., Ha, T. H., & Park, T. K. (2020). Peripapillary intravitreal injection improves AAV-mediated retinal transduction. Molecular Therapy - Methods & Clinical Development, 17(June), 647–656. https://doi.org/10.1016/J.OMTM.2020.03.018
3. Madrakhimov, S., Yang, J., Kim, J., Han, J., & Park, T. (2020). mTOR-dependent dysregulation of autophagy contributes to the retinal ganglion cell loss in streptozotocin-induced diabetic retinopathy. Cell Communication and Signaling, 1–16. https://doi.org/10.1186/s12964-020-00698-4
4. Park, T; Madrakhimov, SB; Yang, J; Ahn, D; Ha, T. (2019). A novel modified deep intravitreal injection improves Adeno-associated virus (AAV)-mediated retinal transduction. Human Gene Therapy, 30(11), A1–A221. https://doi.org/10.1089/hum.2019.29095.abstracts
5. Madrakhimov, S. B., Yang, J. Y., Park, H. Y., & Park, T. K. (2019). Essential Role of mTOR Signaling in Human Retinal Pigment Epithelial Cell Regeneration After Laser Photocoagulation. Lasers in Medical Science, 34(5), 1019–1029. https://doi.org/10.1007/s10103-018-2692-5
6. Yang, J. Y., Madrakhimov, S. B., Ahn, D. H., Chang, H. S., Jung, S. J., Nah, S. K., Park, H. Y., & Park, T. K. (2019). mTORC1 and mTORC2 are differentially engaged in the development of laser-induced CNV. Cell Communication and Signaling, 17(1), 64. https://doi.org/10.1186/s12964-019-0380-0
7. Cho, I. H., Park, S. J., Lee, S. H., Nah, S. K., Park, H. Y., Yang, J. Y., Madrakhimov, S. B., Lyu, J., & Park, T. K. (2019). The role of Wnt/β-catenin signaling in the restoration of induced pluripotent stem cell-derived retinal pigment epithelium after laser photocoagulation. Lasers in Medical Science, 34(3), 571–581. https://doi.org/10.1007/s10103-018-2631-5
8. Lee, S. H., Yang, J. Y., Madrakhimov, S. B., Park, H. Y., Park, K., & Park, T. K. (2019). Adeno-Associated Viral Vector 2 and 9 Transduction Is Enhanced in Streptozotocin-Induced Diabetic Mouse Retina. Molecular Therapy - Methods and Clinical Development, 13(June), 55–66. https://doi.org/10.1016/j.omtm.2018.11.008
9. Jang, S. Y., Cho, I. H., Yang, J. Y., Park, H. Y., Woo, S. E., Madrakhimov, S. B., Chang, H. S., Lyu, J., & Park, T. K. (2019). The retinal pigment epithelial response after retinal laser photocoagulation in diabetic mice. Lasers in Medical Science, 34(1), 179–190. https://doi.org/10.1007/s10103-018-2680-9